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Characterization of tableting properties measured with a multi-functional compaction instrument for several pharmaceutical excipients and actual tablet formulations

Before designing tablet formulations, it is important to understand the “Tableting Properties” of excipients and API (active pharmaceutical ingredient) powders. Those properties refer to “Compressibility”, “Compactability” and “Manufacturability”, which are difficult to evaluate quantitatively. The study evaluates “Tableting Properties” by using a Gamlen benchtop single-punch tablet press – developed to measure these parameters using a single device. The study confirmed the ability of the Gamlen device to evaluate the characteristics of typical pharmaceutical additives.

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